Search on: COLLAGEN TYPE IV 
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Descriptor English:   Collagen Type IV 
Descriptor Spanish:   Colágeno Tipo IV 
Descriptor Portuguese:   Colágeno Tipo IV 
Tree Number:   D12.776.860.300.250.400.100
Definition English:   A non-fibrillar collagen found in the structure of BASEMENT MEMBRANE. Collagen type IV molecules assemble to form a sheet-like network which is involved in maintaining the structural integrity of basement membranes. The predominant form of the protein is comprised of two alpha1(IV) subunits and one alpha2(IV) subunit, however, at least six different alpha subunits can be incorporated into the heterotrimer. 
Indexing Annotation English:   precursors: coord IM with PROCOLLAGEN (IM)
History Note English:   2002; use COLLAGEN 1990-2001; for PROCOLLAGEN TYPE IV use PROCOLLAGEN 1982-2001; for 7S COLLAGEN use COLLAGEN 1982-2001 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   36246 
Unique Identifier:   D024141 

Occurrence in VHL:
 

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